Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 15.76
Human Site: T863 Identified Species: 21.67
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 T863 E A S S S D I T E K S D G R K
Chimpanzee Pan troglodytes XP_507923 1056 119132 T863 E A S S S D I T E K S D G R K
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 F678 Q K K E L D G F L S I L R N N
Dog Lupus familis XP_534964 1334 149091 T1145 E A S S S E I T E K L T E H K
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 T862 K A S S S E I T K K V R E Q S
Rat Rattus norvegicus O55165 796 89797 A621 V R Q D L E E A Q N E Q T R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S891 Q E S K L E S S L Q Q S K T N
Frog Xenopus laevis P28025 1060 119314 T867 G S S V V E I T D R V N A Q R
Zebra Danio Brachydanio rerio NP_775368 955 106984 A780 E Q A V S V R A R L G S S V H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 I873 V D A R Q Q L I T E D R Q R F
Honey Bee Apis mellifera XP_623508 706 80766 D531 D L A N F S I D E T C E L I N
Nematode Worm Caenorhab. elegans P46873 699 78760 L524 D L H G E F E L D R L D Y L D
Sea Urchin Strong. purpuratus P46872 699 78679 M524 E E R E Q E R M D I E E K Y S
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 D878 K S N V A S V D S I V R G G T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 R857 T D V S S L V R S A C D S N E
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 Q904 M S L I D E I Q S Q I E T I S
Red Bread Mold Neurospora crassa P48467 928 102392 R753 L M R D L Q N R C E R V V E L
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 6.6 66.6 N.A. 46.6 6.6 N.A. N.A. 6.6 20 13.3 N.A. 6.6 13.3 6.6 6.6
P-Site Similarity: 100 100 13.3 73.3 N.A. 73.3 26.6 N.A. N.A. 33.3 66.6 20 N.A. 26.6 40 26.6 26.6
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 6.6 N.A. N.A. 20 6.6 0
P-Site Similarity: 40 N.A. N.A. 33.3 33.3 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 18 0 6 0 0 12 0 6 0 0 6 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 6 0 12 0 0 0 0 % C
% Asp: 12 12 0 12 6 18 0 12 18 0 6 24 0 0 6 % D
% Glu: 30 12 0 12 6 42 12 0 24 12 12 18 12 6 12 % E
% Phe: 0 0 0 0 6 6 0 6 0 0 0 0 0 0 6 % F
% Gly: 6 0 0 6 0 0 6 0 0 0 6 0 18 6 0 % G
% His: 0 0 6 0 0 0 0 0 0 0 0 0 0 6 6 % H
% Ile: 0 0 0 6 0 0 42 6 0 12 12 0 0 12 0 % I
% Lys: 12 6 6 6 0 0 0 0 6 24 0 0 12 0 18 % K
% Leu: 6 12 6 0 24 6 6 6 12 6 12 6 6 6 6 % L
% Met: 6 6 0 0 0 0 0 6 0 0 0 0 0 0 0 % M
% Asn: 0 0 6 6 0 0 6 0 0 6 0 6 0 12 18 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 12 6 6 0 12 12 0 6 6 12 6 6 6 12 0 % Q
% Arg: 0 6 12 6 0 0 12 12 6 12 6 18 6 24 6 % R
% Ser: 0 18 36 30 36 12 6 6 18 6 12 12 12 0 18 % S
% Thr: 6 0 0 0 0 0 0 30 6 6 0 6 12 6 6 % T
% Val: 12 0 6 18 6 6 12 0 0 0 18 6 6 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 6 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _